According to RPG.net wiki "only one game has ever been foolish enough to use caltrop dice as its main die mechanic". I assume this is caused by the fact that tetrahedron doesn't roll at all, which makes it true "kill-joy".
Since I have invented a die that rolls like a charm [or rather like cannonball], I hope this might be a good starting point for creating games based on d4 mechanic.
Anybody interested can visit www.tetrosphere.com to have a look or e-mail me for further details. Let's roll!